cathepsin K EC#: 3.4.22.38; ChemWhat Code: 1380748
| Product Name | cathepsin K |
| Example Structure | ![]() |
| Synonyms | Cat K, Cat-K, cath K, cathepsin K, cathepsin O, Cathepsin O2, cathepsin-K, catK, Ctk, CTSK, Human osteoclast cathepsin K, More, OC-2 protein, rhCK |
| EC Number | 3.4.22.38 |
| CAS Registry Number | 94716-09-3 |
| Comments | Prominently expressed in mammalian osteoclasts, and believed to play a role in bone resorption. In peptidase family?C1?(papain family). |
| Cofactor | |
| History | |
| Reactions | Broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg. |
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