cathepsin L EC#: 3.4.22.15; ChemWhat Code: 1380699

Product Name cathepsin L
Example Structure Example Structure of cathepsin L EC#: 3.4.22.15
Synonyms AgCatL, Aldrichina grahami cysteine proteinase, cat L, Cat L-A, Cath L, cath-L, cathepsin L, cathepsin L isoform CRA-b, cathepsin L-A, cathepsin L-A1, cathepsin L-A2, cathepsin L-A3, cathepsin L-B, cathepsin L-like, cathepsin L-like enzyme, cathepsin L-like proteinase, cathepsin L1, cathepsin L1H, cathepsin-L, cathepsin-L T2V, CatL, CATL A IV, CATL-1, CATL-2, CatL1G, CatL1H, CatL5, CL41.5, CPL, cpl-1, CtL, CTSL, CTSL1, CTSL2, Cwp84, human cathepsin L, major excreted protein, MEP, PDP, progesterone-dependent protein, SMCL1, sperm-histone protease
EC Number 3.4.22.15
CAS Registry Number 60616-82-2
Comments A lysosomal enzyme in peptidase family?C1?(papain family) that is readily inhibited by the diazomethane inhibitor Z-Phe-Phe-CHN2?or the epoxide inhibitor E-64.
Cofactor
History
Reactions Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.

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