cathepsin V EC#: 3.4.22.43; ChemWhat Code: 1380757
| Product Name | cathepsin V |
| Example Structure |  |
| Synonyms | cathepsin L2, cathepsin L2/V, cathepsin like 2, cathepsin U, cathepsin V, cathepsin V/L2, CatV, CL2, CTSL2, CTSV, CV/L2, More, stratum corneum thiol protease |
| EC Number | 3.4.22.43 |
| CAS Registry Number | |
| Comments | Cathepsin V is a human lysosomal cysteine endopeptidase of family?C1?(papain family) that is maximally active at pH 5.7 and unstable at neutral pH. Compound E-64, leupeptin and chicken cystatin are inhibitors. Human cathepsin V shows expression restricted to thymus, testis, corneal epithelium and some colon and breast carcinomas. Human gene locus: 9q22.2. |
| Cofactor | |
| History | |
| Reactions | The recombinant enzyme hydrolyzes proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val- Arg-NHMec). |
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