CC-preferring endodeoxyribonuclease EC#: 3.1.21.6; ChemWhat Code: 1379739
| Product Name | CC-preferring endodeoxyribonuclease |
| Example Structure |  |
| Synonyms | Deoxyriboendonuclease, DNA-adenine-transferase, EC 3.1.4.30, endodeoxyribonuclease, endonuclease II, endonuclease NX, endonuclease T, Escherichia coli endonuclease II, Nuclease, endodeoxyribo-, R1Bm EN, R1Bm endonuclease, Redoxyendonuclease, Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease, VirD1/D2 endonuclease |
| EC Number | 3.1.21.6 |
| CAS Registry Number | 37211-67-9 |
| Comments | Prefers CC sites in double-stranded circular and linear DNA. Greater affinity for double-stranded than single-stranded DNA. Produces nicks, generating double-stranded fragments with 5′- and/or 3′-protruding single-stranded tails. Requires magnesium ions for activity. The endonuclease from?Chlorella-like green algae infected with NYs-1 virus 4[1] may be the same enzyme. |
| Cofactor | Mg2+ |
| History | |
| Reactions | Endonucleolytic cleavage to give 5′-phosphooligonucleotide end-products, with a preference for cleavage within the sequence Cc. |
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