CC-preferring endodeoxyribonuclease EC#: 3.1.21.6; ChemWhat Code: 1379739

Product Name CC-preferring endodeoxyribonuclease
Example Structure Example Structure of CC-preferring endodeoxyribonuclease EC#: 3.1.21.6
Synonyms Deoxyriboendonuclease, DNA-adenine-transferase, EC 3.1.4.30, endodeoxyribonuclease, endonuclease II, endonuclease NX, endonuclease T, Escherichia coli endonuclease II, Nuclease, endodeoxyribo-, R1Bm EN, R1Bm endonuclease, Redoxyendonuclease, Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease, VirD1/D2 endonuclease
EC Number 3.1.21.6
CAS Registry Number 37211-67-9
Comments Prefers CC sites in double-stranded circular and linear DNA. Greater affinity for double-stranded than single-stranded DNA. Produces nicks, generating double-stranded fragments with 5′- and/or 3′-protruding single-stranded tails. Requires magnesium ions for activity. The endonuclease from?Chlorella-like green algae infected with NYs-1 virus 4[1] may be the same enzyme.
Cofactor Mg2+
History
Reactions Endonucleolytic cleavage to give 5′-phosphooligonucleotide end-products, with a preference for cleavage within the sequence Cc.

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