chanoclavine-I aldehyde reductase EC#: 1.3.1.100; ChemWhat Code: 1374072
| Product Name | chanoclavine-I aldehyde reductase |
| Example Structure |  |
| Synonyms | EasA, FgaOx3, old yellow enzyme |
| EC Number | 1.3.1.100 |
| CAS Registry Number | |
| Comments | Contains FMN. The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid produced by some fungi of the Trichocomaceae family. The enzyme catalyses the reduction of chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde. This hydrolyses spontaneously to form 6,8-dimethyl-6,7-didehydroergoline, which is converted to festuclavine by EC 1.5.1.44, festuclavine dehydrogenase. |
| Cofactor | FMN |
| History | |
| Reactions | Dihydrochanoclavine-I aldehyde + NADP(+) = chanoclavine-I aldehyde + Nadph. |
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