choloyl-CoA hydrolase EC#: 3.1.2.27; ChemWhat Code: 1379369

Product Name choloyl-CoA hydrolase
Example Structure Example Structure of choloyl-CoA hydrolase EC#: 3.1.2.27
Synonyms acyl-CoA thioesterase, bile acid-CoA thioesterase, chenodeoxycholic acid-CoA thioesterase, chenodeoxycholoyl-coenzyme A thioesterase, choloyl-coenzyme A thioesterase, coenzyme A thioesterase 2, peroxisomal acyl-coA thioesterase, PTE-2
EC Number 3.1.2.27
CAS Registry Number
Comments Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short- and medium- to long-chain acyl-CoAs, and other substrates, including trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched chain acyl-CoAs, all of which are present in peroxisomes. The enzyme is strongly inhibited by CoA and may be involved in controlling CoA levels in the peroxisome [1].
Cofactor
History
Reactions Choloyl-CoA + H(2)O = cholate + CoA.

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