CO-methylating acetyl-CoA synthase EC#: 2.3.1.169; ChemWhat Code: 1376967
| Product Name | CO-methylating acetyl-CoA synthase |
| Example Structure |  |
| Synonyms | ACDS multienzyme complex, acetyl-CoA decarbonylase/synthase multienzyme complex, acetyl-CoA decarboxylase/synthase, Acetyl-CoA synthase, Acetyl-coenzyme A synthase, acetyl-coenzyme A synthase/carbon monoxide dehydrogenase, ACS/CODH, ACSCh, Carbon monoxide dehydrogenase, carbon monoxide dehydrogenase-corrinoid enzyme complex, carbon monoxide dehydrogenase/acetyl coenzyme A synthase, carbon monoxide dehydrogenase/acetyl-CoA synthase, carbon monoxide dehydrogenase/acetyl-coenzyme A synthase, CDH1, Cdh2, CO dehydrogenase, CO dehydrogenase enzyme complex, CO dehydrogenase/acetyl CoA synthase, CO dehydrogenase/acetyl coenzyme A synthase, CO dehydrogenase/acetyl-CoA synthase, CODH, CODH/ACS, CODH/ASC, KSU1_D0226, KSU1_D0227, multienzyme carbon monoxide dehydrogenase complex, multienzyme CO dehydrogenase/acetyl-CoA synthase complex |
| EC Number | 2.3.1.169 |
| CAS Registry Number | |
| Comments | Contains nickel, copper and iron-sulfur clusters. Involved, together with EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin), in the synthesis of acetyl-CoA from CO2 and H2. |
| Cofactor | Ni2+;iron-sulfur;Cu2+ |
| History | |
| Reactions | Acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = Co + CoA + a [methyl- Co(III) corrinoid Fe-S protein]. |
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