CoA-disulfide reductase EC#: 1.8.1.14; ChemWhat Code: 1374685
| Product Name | CoA-disulfide reductase |
| Example Structure |  |
| Synonyms | BACoADR, BB0728, CoA disulfide reductase, CoA-disulfide reductase (NADH), CoA-disulfide reductase (NADH2), CoADR, coenzyme A disulfide reductase, coenzyme A disulphide reductase, coenzyme A-disulfide reductase, NADH2:CoA-disulfide oxidoreductase, NADH:CoA-disulfide oxidoreductase, PH0572 |
| EC Number | 1.8.1.14 |
| CAS Registry Number | 206770-55-0 |
| Comments | A flavoprotein. Not identical with EC 1.8.1.6 (cystine reductase), EC 1.8.1.7 (glutathione-disulfide reductase) or EC 1.8.1.13 (bis-¦Ã-glutamylcystine reductase). The enzyme from the bacterium Staphylococcus aureus has a strong preference for NADPH [3], while the bacterium Bacillus megaterium contains both NADH and NADPH-dependent enzymes [1]. |
| Cofactor | FAD |
| History | |
| Reactions | 2 CoA + NADP(+) = CoA-disulfide + Nadph. |
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