coagulation factor Xa EC#: 3.4.21.6; ChemWhat Code: 1380456
| Product Name | coagulation factor Xa |
| Example Structure |  |
| Synonyms | activated blood-coagulation factor X, activated factor X, activated Stuart-Prower factor, autoprothrombin C, blood coagulation factor X, blood coagulation factor Xa, blood-coagulation factor X, activated, clotting factor Xa, coagulation factor X, coagulation factor Xa, f.Xa, factor X, factor Xa, Fgl2 protein, fX, FXa, hXa, More, oscutarin, plasma thromboplastin, procoagulant factor X, prothrombase, prothrombin activator, prothrombinase, Stuart factor, thrombokinase, thromboplastin, thromboplastin, plasma, trocarin, Trocarin prothrombin activator, VAP, Virus activating protease, Xa |
| EC Number | 3.4.21.6 |
| CAS Registry Number | 9002/5/5 |
| Comments | A blood coagulation factor formed from the proenzyme factor X by limited proteolysis. Factor X is a glycoprotein composed of a heavy chain and a light chain, which are generated from a precursor protein by the excision of the tripeptide RKR and held together by one or more disulfide bonds. The activated factor Xa converts prothrombin to thrombin in the presence of factor Va, Ca2+?and phospholipids. Scutelarin (EC?3.4.21.60) has similar specificity, but does not require factor Va. |
| Cofactor | |
| History | |
| Reactions | Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin. |
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