codeine 3-O-demethylase EC#: 1.14.11.32; ChemWhat Code: 1375117
| Product Name | codeine 3-O-demethylase |
| Example Structure |  |
| Synonyms | codeine O-demethylase, codeine-O-demethylase, CODM |
| EC Number | 1.14.11.32 |
| CAS Registry Number | |
| Comments | Requires Fe2+. Catalyses a step in morphine biosynthesis. The enzyme also catalyses the 3-O-demethylation of thebaine to oripavine, with lower efficiency. |
| Cofactor | Fe2+ |
| History | |
| Reactions | Codeine + 2-oxoglutarate + O(2) = morphine + formaldehyde + succinate + CO(2). |
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