coenzyme F420 hydrogenase EC#: 1.12.98.1; ChemWhat Code: 1374879
| Product Name | coenzyme F420 hydrogenase |
| Example Structure |  |
| Synonyms | 8-hydroxy-5-deazaflavin-reactive hydrogenase, 8-hydroxy-5-deazaflavin-reducing hydrogenase, coenzyme F420-dependent hydrogenase, coenzyme F420-reducing dehydrogenase, deazaflavin-reducing hydrogenase, EC 1.12.99.1, F420-reducing hydrogenase, F420-reducing [NiFe] hydrogenase, F420-reducing [NiFe]-hydrogenase, FRH, FrhABG, hydrogen:(acceptor) oxidoreductase, Mbar_A0449, Mbar_A0450, Mbar_A0452, VhuD |
| EC Number | 1.12.98.1 |
| CAS Registry Number | 9027/5/8 |
| Comments | An iron-sulfur flavoprotein (FAD) containing nickel. The enzyme from some sources contains selenocysteine. The enzyme also reduces the riboflavin analogue of F420, flavins and methylviologen, but to a lesser extent. The hydrogen acceptor coenzyme F420 is a deazaflavin derivative. |
| Cofactor | Ni2+;Fe cation;FAD |
| History | |
| Reactions | H(2) + oxidized coenzyme F420 = reduced coenzyme F420. |
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