complement factor D EC#: 3.4.21.46; ChemWhat Code: 1380538

Product Name complement factor D
Example Structure Example Structure of complement factor D EC#: 3.4.21.46
Synonyms 28 kDa protein, adipocyte, Adipsin, alternative complement pathway component Factor D, C3 convertase activator, C3 proactivator convertase, complement factor D/adipsin and kallikrein-like serine protease, convertase, C3 proactivator, Df, Df protein, endogenous vascular elastase, esterase, properdin factor D, factor D, factor D (complement), fD, PDGF-D, platelet-derived growth factor D, PoDAK, vascular endothelial growth factor, vascular endothelial growth factor D, VEGF-D
EC Number 3.4.21.46
CAS Registry Number 37213-56-2
Comments A component of the alternative pathway of complement activation. This reaction is analogous to the activation of complement component C2 by complement subcomponent C1?s?. In peptidase family?S1?(trypsin family).
Cofactor
History
Reactions Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.

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