complement factor I EC#: 3.4.21.45; ChemWhat Code: 1380535
| Product Name | complement factor I |
| Example Structure |  |
| Synonyms | C3b inactivator, C3b/C4b inactivator, C3bINA, CFI, complement C3b inactivator, complement C3b/C4b inactivator, complement C4b inactivator, complement C4bi, complement compoment C3b inactivator, complement factor I, complement inhibitor factor I, complement regulator factor I, conglutinogen-activating factor C, factor I, factor I-like activity, fI, GcIf-1, GcIf-2, GcIf-3, GcIf-4, IF, serine protease Factor I |
| EC Number | 3.4.21.45 |
| CAS Registry Number | 80295-66-5 |
| Comments | Cleavage of complement subcomponent C3b requires its binding to cofactor factor H or complement receptor CR1; cleavage of iC3b requires complement receptor CR1; cleavage of C4b requires C4b-binding protein. In peptidase family?S1?(trypsin family). |
| Cofactor | |
| History | |
| Reactions | Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage. |
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