cyclic-di-AMP phosphodiesterase EC#: 3.1.4.59; ChemWhat Code: 1379640

Product Name cyclic-di-AMP phosphodiesterase
Example Structure Example Structure of cyclic-di-AMP phosphodiesterase EC#: 3.1.4.59
Synonyms BB0619, CdnD, Dhhp, gdpP, llmg_1816, Lmo0052, MSMEG_2630, NrnA, PDE, PDE1, PDE2, PdeA, PgpH, Rv2837c, SAOUHSC_00015, SPD_1153, SPD_2032, SSU98_2160, YybT
EC Number 3.1.4.59
CAS Registry Number
Comments The enzyme, described from Gram-positive bacteria, degrades the second messenger cyclic di-3′,5′-adenylate. It is a membrane-bound protein that contains a cytoplasmic facing Per-Arnt-Sim (PAS) domain, a modified GGDEF domain, and a DHH/DHHA1 domain, which confers the phosphodiesterase activity. Activity requires Mn2+?and is inhibited by pApA.
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