cyclo(L-leucyl-L-leucyl) synthase EC#: 2.3.2.22; ChemWhat Code: 1377178
| Product Name | cyclo(L-leucyl-L-leucyl) synthase |
| Example Structure |  |
| Synonyms | cLL synthase, cyclodileucine synthase, YvmC |
| EC Number | 2.3.2.22 |
| CAS Registry Number | |
| Comments | The reaction proceeds following a ping-pong mechanism forming a covalent intermediate between an active site serine and the first L-leucine residue [2]. The proteins from bacteria of the genus Bacillus also form small amounts of cyclo(L-phenylalanyl-L-leucyl) and cyclo(L-leucyl-L-methionyl) [1]. |
| Cofactor | |
| History | |
| Reactions | 2 L-leucyl-tRNA(Leu) = 2 tRNA(Leu) + cyclo(L-leucyl-L-leucyl). |
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