cystathionine gamma-synthase EC#: 2.5.1.48; ChemWhat Code: 1377951
| Product Name | cystathionine gamma-synthase |
| Example Structure |  |
| Synonyms | AtCGS, CGS, CGS1, CS,26, cystathionine synthase, cystathionine synthetase, cystathionine-gamma-synthase, EC 4.2.99.9, homoserine O-transsuccinylase, homoserine transsuccinylase, HTS, MetB, O-succinyl-L-homoserine succinate-lyase (adding cysteine), O-succinylhomoserine (Thiol)-lyase, O-succinylhomoserine synthase, O-succinylhomoserine synthetase, synthase, cystathionine gamma- |
| EC Number | 2.5.1.48 |
| CAS Registry Number | 9030-70-0 |
| Comments | A pyridoxal-phosphate protein. Also reacts with hydrogen sulfide and methanethiol as replacing agents, producing homocysteine and methionine, respectively. In the absence of thiol, can also catalyse ¦Â,¦Ã-elimination to form 2-oxobutanoate, succinate and ammonia. |
| Cofactor | pyridoxal 5′-phosphate |
| History | |
| Reactions | O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate. |
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