cysteine desulfurase EC#: 2.8.1.7; ChemWhat Code: 1379060
| Product Name | cysteine desulfurase |
| Example Structure |  |
| Synonyms | c-ISCS, CD0387, CpNifS, CSD, CsdA, CsdB, CysD, cysteine desulfurase, cysteine desulphurase, cysteine:SufU sulfurtransferase, cysteinedesulfurylase, DndA, hAPE, IscS, L-cysteine desulfurase, Lecsl, Nfs, Nfs1, Nfs1p, Nfs2, NIFS, NifS4, Slr0077, Slr0077/SufS, Slr0387, SufS, SufS2 |
| EC Number | 2.8.1.7 |
| CAS Registry Number | |
| Comments | A pyridoxal-phosphate protein. The sulfur from free?L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors. The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin) [2]. In?Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation [1]. |
| Cofactor | pyridoxal 5′-phosphate |
| History | |
| Reactions | L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor. |
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