Cytochrome C CAS#: 9007-43-6; ChemWhat Code: 81344
Identification
Product Name | Cytochrome C |
IUPAC Name | 3-[8,13-bis[1-[2-amino-3-(methylamino)-3-oxopropyl]sulfanylethyl]-18-(2-carboxyethyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(2+) |
Molecular Structure | ![]() |
CAS Registry Number | 9007-43-6 |
EINECS Number | 232-700-9 |
MDL Number | MFCD00130890 |
Synonyms | (1Z,6Z,12Z,17Z)-4,9-Bis(1-{[2-amino-3-(méthylamino)-3-oxopropyl]sulfanyl}éthyl)-15,19-bis(2-carboxyéthyl)-5,10,14,20-tétraméthyl-21,22,23,24-tétraazapentacyclo[16.2.1.13,6.18,11.113,16]tétracosa;-1,3(24),4,6,8,10,12,14,16(22),17,19-undécaène-21,23-diide de fer(2+) [French] [ACD/IUPAC Name];21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis[1-[[2-amino-3-(methylamino)-3-oxopropyl]thio]ethyl]-3,8,13,17-tetramethyl-, iron(2+) salt;(1:1) [ACD/Index Name];Eisen(2+)-(1Z,6Z,12Z,17Z)-4,9-bis(1-{[2-amino-3-(methylamino)-3-oxopropyl]sulfanyl}ethyl)-15,19-bis(2-carboxyethyl)-5,10,14,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.13,6.18,11.113,16;]tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaen-21,23-diid [German] [ACD/IUPAC Name];Iron(2+) (1Z,6Z,12Z,17Z)-4,9-bis(1-{[2-amino-3-(methylamino)-3-oxopropyl]sulfanyl}ethyl)-15,19-bis(2-carboxyethyl)-5,10,14,20-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.13,6.18,11.113,16];tetracosa-1,3(24),4,6,8,10,12,14,16(22),17,19-undecaene-21,23-diide [ACD/IUPAC Name];[9007-43-6];9007-43-6 [RN];Cytochrome C [JAN];Cytorest [Trade name];MFCD00130890 |
Molecular Formula | C42H52FeN8O6S2 |
Molecular Weight | 884.9 |
InChI | InChI=1S/C42H54N8O6S2.Fe/c1-19-25(9-11-37(51)52)33-16-34-26(10-12-38(53)54)20(2)30(48-34)14-35-40(24(6)58-18-28(44)42(56)46-8)22(4)32(50-35)15-36-39(21(3)31(49-36)13-29(19)47-33)23(5)57-17-27(43)41(55)45-7;/h13-16,23-24,27-28H,9-12,17-18,43-44H2,1-8H3,(H6,45,46,47,48,49,50,51,52,53,54,55,56);/q;+2/p-2/b29-13-,30-14-,31-13-,32-15-,33-16-,34-16-,35-14-,36-15-; |
InChI Key | WFVBWSTZNVJEAY-UHFFFAOYSA-L |
Canonical SMILES | CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C(C)SCC(C(=O)NC)N)C)C(C)SCC(C(=O)NC)N)C)CCC(=O)O)CCC(=O)O.[Fe+2] |
Patent Information | ||
No data available |
Physical Data
Appearance | Dark-rea crystalline or amorphouspowder |
Melting Point | 300 °C |
Solubility | 100 g/L (20 ºC) |
Water Solubility | H2O: 10 mg/mL, clear, dark red-brown |
Spectra
Route of Synthesis (ROS)
No data available |
Safety and Hazards
Pictogram(s) | |
Signal | Warning |
GHS Hazard Statements | H302: Harmful if swallowed [Warning Acute toxicity, oral] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] Information may vary between notifications depending on impurities, additives, and other factors. |
Precautionary Statement Codes | P261, P264, P270, P271, P301+P312, P304+P312, P304+P340, P312, P330, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) For more detailed information, please visit ECHA C&L website |
Other Data
Transportation | Not dangerous goods |
Under 2-8℃ and away from light | |
HS Code | 294200 |
Storage | Store at -15℃ for a long time, away from light and moisture. |
Shelf Life | 1 year |
Market Price | USD 79/g |
Use Pattern |
Cytochrome c has been identified as an important mediator in apoptotic pathways. The release of mitochondrial cytochrome c into the cytoplasm stimulates apoptosis and is commonly used as an indicator of the apoptotic process in the cell. Investigation on the effect of Paris Saponin I (PS I) on human gastric carcinoma cell growth (SGC7901 cells) have shown an elevated level cytoplasmic cytochrome c. Results are an inhibition of proliferation in SGC7901 cells by inducing mitochondria-dependent apoptosis through cytochrome c. |
The ready interconversion of cytochrome c between ferrous and ferric states makes it an efficient biological electron carrier. It plays a vital role in cellular oxidations in both plants and animals. Generally regarded as a universal link in the respiratory chain, it forms the essential electron-bridge between the respirable substrates and oxygen. |
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