D-2-hydroxyacid dehydrogenase (quinone) EC#: 1.1.5.10; ChemWhat Code: 1373654

Product Name D-2-hydroxyacid dehydrogenase (quinone)
Example Structure Example Structure of D-2-hydroxyacid dehydrogenase (quinone) EC#: 1.1.5.10
Synonyms (R)-2-hydroxy acid dehydrogenase, (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase, D-lactate dehydrogenase, DLD
EC Number 1.1.5.10
CAS Registry Number
Comments The enzyme from mammalian kidney contains one mole of FAD per mole of enzyme.(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.
Cofactor FAD
History
Reactions (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol.

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