D-2-hydroxyglutarate dehydrogenase EC#: 1.1.99.39; ChemWhat Code: 1373718

Product Name D-2-hydroxyglutarate dehydrogenase
Example Structure Example Structure of D-2-hydroxyglutarate dehydrogenase EC#: 1.1.99.39
Synonyms 2-hydroxyglutarate dehydrogenase, AtD-2HGDH, D-2-HGA, D2-hydroxyglutarate dehydrogenase, D2HGDH
EC Number 1.1.99.39
CAS Registry Number
Comments Contains FAD. The enzyme has no activity with NAD+ or NADP+, and was assayed in vitro using artificial electron acceptors. It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and meso-tartrate, and no activity with the (S) isomers. The mammalian enzyme is stimulated by Zn2+, Co2+ and Mn2+.
Cofactor FAD
History
Reactions (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.

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