D-arabinose isomerase EC#: 5.3.1.3; ChemWhat Code: 1383186

Product Name D-arabinose isomerase
Example Structure Example Structure of D-arabinose isomerase EC#: 5.3.1.3
Synonyms D-AI, D-arabinose aldose-ketose-isomerase, D-Arabinose isomerase, D-arabinose ketol-isomerase, D-Arabinose(L-fucose) isomerase, EC 5.1.3.25, Isomerase, arabinose, L-Fucose isomerase
EC Number 5.3.1.3
CAS Registry Number 9023-81-8
Comments Requires a divalent metal ion (the enzyme from the bacterium?Escherichia coli?prefers Mn2+). The enzyme binds the closed form of the sugar and catalyses ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism [3]. The enzyme catalyses the aldose-ketose isomerization of several sugars. Most enzymes also catalyse the reaction of EC?5.3.1.25,?L-fucose isomerase [3]. The enzyme from the bacterium?Falsibacillus pallidus?also converts?D-altrose to?D-psicose [4].?cf. EC?5.3.1.4,?L-arabinose isomerase.
Cofactor Mn2+
History
Reactions D-arabinose = D-ribulose.

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