| Product Name |
D-glycero-beta-D-manno-heptose-7-phosphate kinase |
| Example Structure |
 |
| Synonyms |
bifunctional D-beta-D-heptose-7-phosphate kinase/D-beta-dheptose-1-phosphate adenylyltransferase, D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase, D-beta-D-heptose 7-phosphotransferase, D-beta-D-heptose-7-phosphate kinase, glycero-manno-heptose 7-phosphate kinase, heptose 7-phosphate kinase, HldE, HldE1 heptokinase |
| EC Number |
2.7.1.167 |
| CAS Registry Number |
|
| Comments |
The bifunctional protein?hldE?includes?D-glycero-¦Â-D-manno-heptose-7-phosphate kinase and?D-glycero-¦Â-D-manno-heptose 1-phosphate adenylyltransferase activity (cf. EC?2.7.7.70). The enzyme is involved in biosynthesis of ADP-L-glycero-¦Â-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core in Gram-negative bacteria. The enzyme selectively produces?D-glycero-¦Â-D-manno-heptose 1,7-bisphosphate [5]. |
| Cofactor |
|
| History |
|
| Reactions |
D-glycero-beta-D-manno-heptose 7-phosphate + Atp = D-glycero-beta-D- manno-heptose 1,7-bisphosphate + Adp. |
