D-lactate dehydratase EC#: 4.2.1.130; ChemWhat Code: 1382436
| Product Name | D-lactate dehydratase |
| Example Structure |  |
| Synonyms | DJ-1, DJ-1 glyoxalase, DJ-1a, DJ-1b, DJ-1c, DJ-1e, DJ-1f, GLO3, glutathione-independent glyoxalase III, glyoxalase III, glyoxylase III, GSH-independent glyoxalase III, hchA, Hsp31, Hsp3101, Hsp3102, hsp3106, More, PfpI, protein DJ-1 homolog A, protein DJ-1 homolog B, protein DJ-1 homolog C, protein DJ-1 homolog E, protein DJ-1 homolog F, SpDJ-1, yajL, yhbO |
| EC Number | 4.2.1.130 |
| CAS Registry Number | |
| Comments | The enzyme, described from the fungi?Candida albicans?and?Schizosaccharomyces pombe, converts 2-oxopropanal to (R)-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalysed by EC?4.4.1.5, lactoylglutathione lyase and EC?3.1.2.6, hydroxyacylglutathione hydrolase. |
| Cofactor | |
| History | |
| Reactions | (R)-lactate = methylglyoxal + H(2)O. |
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