dCTP deaminase (dUMP-forming) EC#: 3.5.4.30; ChemWhat Code: 1381473

Product Name dCTP deaminase (dUMP-forming)
Example Structure Example Structure of dCTP deaminase (dUMP-forming) EC#: 3.5.4.30
Synonyms DCD-DUT, DCD:DUT, dcdB, DCDDUT, dCTP deaminase-dUTP pyrophosphatase, dCTP deaminase-dUTPase, MJ0430
EC Number 3.5.4.30
CAS Registry Number
Comments Requires Mg2+. Is highly specific for dCTP as substrate as dCMP, CTP, CDP, CMP, cytosine or deoxycytosine are not deaminated. While most bacteria require two enzymes to form dUMP from dCTP (EC?3.5.4.13, dCTP deaminase and EC?3.6.1.23, dUTP diphosphatase), the archaeon?Methanocaldococcus jannaschii?uses a single enzyme to carry out both functions. This enzyme can also act as a dUTP diphosphatase, but more slowly.
Cofactor Mg2+
History
Reactions dCTP + 2 H(2)O = dUMP + diphosphate + NH(3).

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