deuterolysin EC#: 3.4.24.39; ChemWhat Code: 1381023
| Product Name | deuterolysin |
| Example Structure |  |
| Synonyms | Acid metalloproteinase, AsaP1, aspzincin, Deuterolysin, EC 3.4.24.4, Mep-1 like, Mep-2 like, Mep-2-like, Mep1-like, Mep2, Mep2-like, Mep3, Mep3-like, Mep4, Mep4-1 like, Mep4-like, Mep5, Mep5-like, Mep6, Mep6-like, Mep7, Mep7-like, Mep8, Mep8-like, Microbial neutral proteinase II, Neutral proteinase II, NPII, Penicillium roqueforti metalloproteinase, Penicillium roqueforti protease II, Proteinase, Penicillium roqueforti metallo- |
| EC Number | 3.4.24.39 |
| CAS Registry Number | 73562-33-1 |
| Comments | Proteolytic activity found in?Penicillium roqueforti?[4],?P. caseicolum?[4],?Aspergillus sojae?[3] and?A. oryzae?[1, 5]. Optimum pH of 5 for digesting various proteins. Strong action on protamine and histones. Insensitive to phosphoramidon. About 20 kDa. A distinct?Aspergillus sojae?endopeptidase is larger and has a neutral pH optimum. Type example of peptidase family?M35. Formerly included in EC?3.4.24.4. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Preferential cleavage of bonds with hydrophobic residues in P1′; also 3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain. |
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