dihydrofolate reductase EC#: 1.5.1.3; ChemWhat Code: 1374353

Product Name dihydrofolate reductase
Example Structure Example Structure of dihydrofolate reductase EC#: 1.5.1.3
Synonyms 5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, 7,8-dihydrofolate reductase, bifunctional TS-DHFR, BmDHFR, dehydrogenase, tetrahydrofolate, DFR-TS, DHFR, DHFR type IIIC, DHFR-TS, DHFR2, DHFRL1, DHFRLS, dihydrofolate reductase, dihydrofolate reductase-like, dihydrofolate reductase-thymidylate synthase, dihydrofolate reductase:thymidylate synthase, dihydrofolic acid reductase, dihydrofolic reductase, EC 1.5.1.4, ecDHFR, folA3, folic acid reductase, folic reductase, FolM, hDHFR, hDHFR-1, hDHFR-2, HjDHFR, hvDHFR1, hvDHFR2, LBRM_06_0830, mDHFR, mjDHFR, More, myDHFR, NADPH-dihydrofolate reductase, pcDHFR, ppDHFR, pteridine reductase:dihydrofolate reductase, R-plasmid-encoded dihydrofolate reductase, R67 DHFR, R67 dihydrofolate reductase, reductase, dihydrofolate, S3DHFR, Smdhfr, Smp 175230, spDHFR, svDHFR, tetrahydrofolate dehydrogenase, thymidylate synthase-dihydrofolate reductase, thymidylate synthetase-dihydrofolate reductase, Trimethoprim resistance protein, TS-DHFR
EC Number 1.5.1.3
CAS Registry Number 9002/3/3
Comments The enzyme from animals and some micro-organisms also slowly reduces folate to 5,6,7,8-tetrahydrofolate.
Cofactor
History
Reactions 5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + Nadph.

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