dihydromethanopterin reductase [NAD(P)+] EC#: 1.5.1.47; ChemWhat Code: 1374423

Product Name dihydromethanopterin reductase [NAD(P)+]
Example Structure Example Structure of dihydromethanopterin reductase [NAD(P)+] EC#: 1.5.1.47
Synonyms dihydromethanopterin reductase, DmrA, H2MPT reductase
EC Number 1.5.1.47
CAS Registry Number
Comments The enzyme, characterized from the bacterium Methylobacterium extorquens, is involved in biosynthesis of dephospho-tetrahydromethanopterin. The specific activity with NADH is 15% of that with NADPH at the same concentration [1]. It does not reduce 7,8-dihydrofolate (cf. EC 1.5.1.3, dihydrofolate reductase).
Cofactor
History
Reactions 5,6,7,8-tetrahydromethanopterin + NAD(P)(+) = 7,8-dihydromethanopterin + NAD(P)H.

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