dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase EC#: 3.1.2.31; ChemWhat Code: 1379375
Product Name | dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase |
Example Structure | |
Synonyms | LovG |
EC Number | 3.1.2.31 |
CAS Registry Number | |
Comments | Dihydromonacolin L acid is synthesized while bound to an acyl-carrier protein domain of the lovastatin nonaketide synthase (EC?2.3.1.161). Since that enzyme lacks a thioesterase domain, release of the dihydromonacolin L acid moiety from the polyketide synthase requires this dedicated enzyme. |
Cofactor | |
History | |
Reactions | Dihydromonacolin L-[lovastatin nonaketide synthase] + H(2)O = holo- [lovastatin nonaketide synthase] + dihydromonacolin L acid. |
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