dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase EC#: 3.1.2.31; ChemWhat Code: 1379375
| Product Name | dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase |
| Example Structure | ![]() |
| Synonyms | LovG |
| EC Number | 3.1.2.31 |
| CAS Registry Number | |
| Comments | Dihydromonacolin L acid is synthesized while bound to an acyl-carrier protein domain of the lovastatin nonaketide synthase (EC?2.3.1.161). Since that enzyme lacks a thioesterase domain, release of the dihydromonacolin L acid moiety from the polyketide synthase requires this dedicated enzyme. |
| Cofactor | |
| History | |
| Reactions | Dihydromonacolin L-[lovastatin nonaketide synthase] + H(2)O = holo- [lovastatin nonaketide synthase] + dihydromonacolin L acid. |
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![Example Structure of dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase EC#: 3.1.2.31](/wp-content/uploads/enzyme-structure/3.1.2.31.jpg)