dihydroorotate dehydrogenase (NADP+) EC#: 1.3.1.15; ChemWhat Code: 1373961

Product Name dihydroorotate dehydrogenase (NADP+)
Example Structure Example Structure of dihydroorotate dehydrogenase (NADP+) EC#: 1.3.1.15
Synonyms reductase, orotate (reduced nicotinamide adenine dinucleotide phosphate), triphosphopyridine-linked dihydroorotic dehydrogenase
EC Number 1.3.1.15
CAS Registry Number 37255-27-9
Comments Binds FMN and FAD [2]. Other class 1 dihydroorotate dehydrogenases use either fumarate (EC 1.3.98.1) or NAD+ (EC 1.3.1.14) as electron acceptor. The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2) uses quinone as electron acceptor.
Cofactor FMN;FAD
History
Reactions (S)-dihydroorotate + NADP(+) = orotate + Nadph.

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