dihydroorotate dehydrogenase (NADP+) EC#: 1.3.1.15; ChemWhat Code: 1373961
Product Name | dihydroorotate dehydrogenase (NADP+) |
Example Structure | |
Synonyms | reductase, orotate (reduced nicotinamide adenine dinucleotide phosphate), triphosphopyridine-linked dihydroorotic dehydrogenase |
EC Number | 1.3.1.15 |
CAS Registry Number | 37255-27-9 |
Comments | Binds FMN and FAD [2]. Other class 1 dihydroorotate dehydrogenases use either fumarate (EC 1.3.98.1) or NAD+ (EC 1.3.1.14) as electron acceptor. The membrane bound class 2 dihydroorotate dehydrogenase (EC 1.3.5.2) uses quinone as electron acceptor. |
Cofactor | FMN;FAD |
History | |
Reactions | (S)-dihydroorotate + NADP(+) = orotate + Nadph. |
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