dihydrophenazinedicarboxylate synthase EC#: 1.10.3.16; ChemWhat Code: 1374804

Product Name dihydrophenazinedicarboxylate synthase
Example Structure Example Structure of dihydrophenazinedicarboxylate synthase EC#: 1.10.3.16
Synonyms Bcep18194_B1572, phzG
EC Number 1.10.3.16
CAS Registry Number
Comments Requires FMN. The enzyme, isolated from the bacteria Pseudomonas fluorescens 2-79 and Burkholderia lata 383, is involved in biosynthesis of the reduced forms of phenazine, phenazine-1-carboxylate, and phenazine-1,6-dicarboxylate, where it catalyses multiple reactions. The enzyme, isolated from the bacteria Pseudomonas fluorescens 2-79 and Burkholderia lata 383, is involved in biosynthesis of the reduced forms of phenazine, phenazine-1-carboxylate, and phenazine-1,6-dicarboxylate, where it catalyses multiple reactions.
Cofactor FMN
History
Reactions (1) (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O(2) = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H(2)O(2). (2) (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + O(2) = (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate + H(2)O(2). (3) (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O(2) = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H(2)O(2). (4) (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O(2) = (10aS)-5,10- dihydrophenazine-1-carboxylate + H(2)O(2).

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