DROMETRIZOLE TRISILOXANE CAS#: 155633-54-8; ChemWhat Code: 34491

IdentificationPhysical DataSpectra
Route of Synthesis (ROS)Safety and HazardsOther Data

Identification

Product NameDROMETRIZOLE TRISILOXANE
IUPAC Name2-(benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[methyl-bis(trimethylsilyloxy)silyl]propyl]phenol
Molecular StructureStructure of Drometrizole Trisiloxane(Mexoryl XL) CAS 155633-54-8
CAS Registry Number 155633-54-8
EINECS NumberNo data available
MDL NumberMFCD22373626
Beilstein Registry Number11343300
Synonymsdrometrizole trisiloxane, 2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)-oxy]disiloxanyl]propyl]phenol, 2-(2H-1,2,3-benzotriazol-2-yl)-4-methyl-6-(2-methyl-3-{1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl}propyl)phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]-1-disiloxanyl]propyl]phenol, silatrizole, 2-(2H-benzotriazol-2-yl)-4-methyl-6-{2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxyl]-disiloxanyl]-propyl}-phenol, (2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]-phenol)
Molecular FormulaC24H39N3O3Si3
Molecular Weight501.841
InChIInChI=1S/C24H39N3O3Si3/c1-18-14-20(15-19(2)17-33(9,29-31(3,4)5)30-32(6,7)8)24(28)23(16-18)27-25-21-12-10-11-13-22(21)26-27/h10-14,16,19,28H,15,17H2,1-9H3
InChI KeyHUVYTMDMDZRHBN-UHFFFAOYSA-N
Canonical SMILESn1c3ccccc3nn1c2cc(cc(c2O)CC(C)C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C)C
Patent Information
Patent IDTitlePublication Date
WO2018/104249PROCESS FOR PURIFYING OR DRYING COMPOUNDS COMPRISING 2-HYDROXYPHENYL BENZOTRIAZOLE FUNCTIONS AND SILOXANE FUNCTIONS2018
US2014/44654COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES2014
US2013/204006PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS2013

Physical Data

AppearanceOff-white to white powder
SolubilityNo data available
Flash PointNo data available
Refractive indexNo data available
SensitivityNo data available

Spectra

DROMETRIZOLE TRISILOXANE CAS#: 155633-54-8 HPLCHPLC of Drometrizole Trisiloxane(Mexoryl XL) CAS 155633-54-8
Absorption Maxima (UV/VIS), nm
344

Route of Synthesis (ROS)

Route of Synthesis (ROS) of DROMETRIZOLE TRISILOXANE CAS 155633-54-8
Route of Synthesis (ROS) of DROMETRIZOLE TRISILOXANE CAS 155633-54-8
ConditionsYield
platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex In ethyl acetate at 50 – 60℃; Product distribution / selectivity; Inert atmosphere; Reflux;89%
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex In ethyl acetate Solvent; Concentration; Inert atmosphere; Reflux;89%
With platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex In ethyl acetate at 60℃; for 6.5h; Industrial scale;

Safety and Hazards

GHS Hazard StatementsNot Classified
Precautionary Statement CodesP260, P261, P264, P270, P271, P273, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P311, P312, P314, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P391, P403+P233, P405, and P501
(The corresponding statement to each P-code can be found at the GHS Classification page.)

Other Data

TransportationNONH for all modes of transport
Under the room temperature and away from light
HS CodeNo data available
StorageUnder the room temperature and away from light
Shelf Life2 years
Market PriceUSD
Druglikeness
Lipinski rules component
Molecular Weight501.848
logP9.055
HBA5
HBD1
Matching Lipinski Rules2
Veber rules component
Polar Surface Area (PSA)69.4
Rotatable Bond (RotB)9
Matching Veber Rules2
Use Pattern
DROMETRIZOLE TRISILOXANE CAS#: 155633-54-8 is a chemical sunscreen agent.
DROMETRIZOLE TRISILOXANE CAS#: 155633-54-8 as ultraviolet (UV) blocker in a composition used in inhibition of the onset of light-induced immunological skin symptoms
DROMETRIZOLE TRISILOXANE CAS#: 155633-54-8 is photoprotective agent of cosmetic composition comprising an extract of Emblica officinalis, a hydroxy acid, and N-substituted aminosulfonic acid useful for the depigmentation of skin
DROMETRIZOLE TRISILOXANE CAS#: 155633-54-8 and Mexoryl SX are often used together to achieve a better synergistic sunscreen effect..
UV screening agent of composition comprising DHEA or its biological precursor or metabolic derivative useful for the pro-pigmenting human skin

Buy Reagent

No reagent supplier? Send quick inquiry to ChemWhat
Want to be listed here as a reagent supplier? (Paid service) Click here to contact ChemWhat

Approved Manufacturers

Apnoke Scientific Ltdhttp://www.apnoke.com/
Want to be listed as an approved manufacturer (Requires approvement)? Please download and fill out this form and send back to approved-manufacturers@chemwhat.com

Other Suppliers

Watson International Limited Visit Watson Official Website

Contact Us for Other Help

Contact us for other information or services Click here to contact ChemWhat