dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase EC#: 2.6.1.106; ChemWhat Code: 1378272

Product Name dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
Example Structure Example Structure of dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase EC#: 2.6.1.106
Synonyms dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose transaminase, DesV
EC Number 2.6.1.106
CAS Registry Number
Comments A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-¦Á-D-desosamine, a sugar found in several bacterial macrolide antibiotics including erythromycin, megalomicin A, mycinamicin II, and oleandomycin. The reaction occurs in the reverse direction.
Cofactor pyridoxal 5′-phosphate
History
Reactions dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-3- dehydro-4,6-deoxy-alpha-D-glucose + L-glutamate.

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