elongation factor 2 kinase EC#: 2.7.11.20; ChemWhat Code: 1379024
| Product Name | elongation factor 2 kinase |
| Example Structure |  |
| Synonyms | Ca2+/calmodulin-dependent kinase III, Ca2+/calmodulin¨Cdependent kinase III, calcium/calmodulin-dependent protein kinase III, eEF-2 kinase, EEF-2K, eEF2 kinase, eEF2-kinase, eEF2K, EF-2K, EF2K, eIF2alpha kinase, elongation factor 2 kinase, elongation factor-2 kinase, eukaryotic elongation factor 2 kinase, eukaryotic elongation factor-2 kinase, eukaryotic translation initiation factor 2alpha kinase, GCN2, GCN2 eIF2alpha kinase, GCN2 kinase, general control nonderepressible 2 kinase, More, TaGCN2 |
| EC Number | 2.7.11.20 |
| CAS Registry Number | |
| Comments | Requires Ca2+?and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC?2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+?[1,2]. |
| Cofactor | Ca2+ |
| History | |
| Reactions | Atp + [elongation factor 2] = adp + [elongation factor 2] phosphate. |
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