endothelin-converting enzyme 1 EC#: 3.4.24.71; ChemWhat Code: 1381073
| Product Name | endothelin-converting enzyme 1 |
| Example Structure |  |
| Synonyms | ECE, ECE-1, ECE-1b, ECE-3, ECE1, endothelin converting enzyme, endothelin converting enzyme-1, Endothelin-converting enzyme, endothelin-converting enzyme 1, endothelin-converting enzyme 1 (ECE-1), endothelin-converting enzyme I, endothelin-converting enzyme-1, endothelin-converting-enzyme-1, ET converting enzyme, hECE-1, More, sECE, solECE-1 |
| EC Number | 3.4.24.71 |
| CAS Registry Number | 138238-81-0 |
| Comments | A phosphoramidon-sensitive metalloendopeptidase in peptidase family?M13?(neprilysin family). An integral membrane protein predominantly of endothelial cells, which generates the potent vasoconstrictor endothelin 1 from its inactive precursor. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1 |
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