enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) EC#: 1.3.1.39; ChemWhat Code: 1373991

Product Name enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
Example Structure Example Structure of enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) EC#: 1.3.1.39
Synonyms acyl-ACP dehydrogenase, enoyl-ACP reductase, enoyl-ACP reductase III, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate) reductase, FabI, FabK, FabL, NADPH 2-enoyl Co A reductase, PG1416
EC Number 1.3.1.39
CAS Registry Number 37251-09-5 (same number as EC 1.3.1.10)
Comments This enzyme completes each cycle of fatty acid elongation by catalysing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to an acyl-carrier protein. It is one of the activities of EC 2.3.1.85, animal fatty-acid synthase system. The mammalian enzyme is Re-specific with respect to NADP+ [cf. EC 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) and and EC 1.3.1.104, enoyl-[acyl-carrier-protein] reductase (NADPH)].
Cofactor
History
Reactions An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl- carrier protein] + Nadph.

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