enoyl-CoA hydratase 2 EC#: 4.2.1.119; ChemWhat Code: 1382420
| Product Name | enoyl-CoA hydratase 2 |
| Example Structure |  |
| Synonyms | (3R)-hydroxyacyl-CoA dehydrogenase/2-enoyl-CoA hydratase 2, (R)-specific ECH, (R)-specific enoyl coenzyme A hydratase, (R)-specific enoyl-CoA hydratase, (R)-specific enoyl-coenzyme A hydratase, 2-enoyl-CoA hydratase, 2-enoyl-CoA hydratase 2, 2-enoyl-hydratase 2, 2E-enoyl-CoA hydratase 2, At1g76150, AtECH2, D-(-)-3-hydroxyacyl-CoA hydro-lyase, D-3-hydroxyacyl-CoA dehydratase, D-3-hydroxyacyl-CoA hydro-lyase, D-bifunctional enzyme, D-BP, D-specific 2-trans-enoyl-CoA hydratase, ECH-2, ECH2, enoyl-CoA hydratase 2, HFX_1483, hydratase 2, MaoC, MaoC-like protein, MFE-2, MFE2, MFE2 hydratase, Mfe2p [CtMfe2p(dha+bdelta)], multifunctional enzyme type 2, multifunctional enzyme type 2 hydratase, perMFE-II, peroxisomal enoyl-CoA hydratase 2, phaJ, PhaJ1, PhaJ1Pa, PhaJ1Pp, PhaJ4, PhaJ4aRe, PhaJ4bRe, PhaJ4cRe, PhaJAc, PhaJYB4, R-ECH, R-hydratase, R-specific enoyl coenzyme A hydratase, R-specific enoyl-CoA hydratase |
| EC Number | 4.2.1.119 |
| CAS Registry Number | |
| Comments | This enzyme catalyses a hydration step in peroxisomal ¦Â-oxidation. The human multifunctional enzyme type 2 (MFE-2) is a 79000 Da enzyme composed of three functional units: (3R)-hydroxyacyl-CoA dehydrogenase, 2-enoyl-CoA hydratase 2 and sterol carrier protein 2-like units [1]. The enzymes from?Aeromonas caviae?[4] and?Arabidopsis thaliana?[5] are monofunctional enzymes. 2-Enoyl-CoA hydratase 3 from?Candida tropicalis?is a part from multifunctional enzyme type 2 [3]. |
| Cofactor | |
| History | |
| Reactions | (3R)-3-hydroxyacyl-CoA = (2E)-2-enoyl-CoA + H(2)O. |
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