enzyme-thiol transhydrogenase (glutathione-disulfide) EC#: 1.8.4.7; ChemWhat Code: 1374722
| Product Name | enzyme-thiol transhydrogenase (glutathione-disulfide) |
| Example Structure | ![]() |
| Synonyms | DnaJ, enzyme-thiol transhydrogenase (oxidized glutathione), glutathione-dependent thiol:disulfide oxidoreductase, thiol-disulfide oxidoreductase, thiol:disulfide oxidoreductase, thiol:disulphide oxidoreductase, YkuV, [xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase |
| EC Number | 1.8.4.7 |
| CAS Registry Number | 85030-79-1 |
| Comments | Converts EC 1.17.1.4 xanthine dehydrogenase into EC 1.17.3.2 xanthine oxidase in the presence of glutathione disulfide; also reduces the disulfide bond of ricin. Not inhibited by Cu2+ or thiol reagents. |
| Cofactor | |
| History | |
| Reactions | [Xanthine dehydrogenase] + glutathione disulfide = [xanthine oxidase] + 2 glutathione. |
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