epi-isozizaene synthase EC#: 4.2.3.37; ChemWhat Code: 1382608

Product Name epi-isozizaene synthase
Example Structure Example Structure of epi-isozizaene synthase EC#: 4.2.3.37
Synonyms EIZS, epi-isozizaene synthase, SAV_3032, SCO5222 protein, TPS2
EC Number 4.2.3.37
CAS Registry Number
Comments Requires Mg2+?for activity. The displacement of the diphosphate group of farnesyl diphosphate occurs with retention of configuration [1]. In the soil-dwelling bacterium?Streptomyces coelicolor?A3(2), the product of this reaction is used by EC?1.14.13.106,?epi-isozizaene 5-monooxygenase, to produce the sesquiterpene antibiotic albaflavenone [2].
Cofactor Mg2+
History
Reactions (2E,6E)-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.

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