erythrose-4-phosphate dehydrogenase EC#: 1.2.1.72; ChemWhat Code: 1373830

Product Name erythrose-4-phosphate dehydrogenase
Example Structure Example Structure of erythrose-4-phosphate dehydrogenase EC#: 1.2.1.72
Synonyms E4P dehydrogenase, E4PD, E4PDH, epd, Epd dehydrogenase, erythrose 4-phosphate dehydrogenase, gap2, GapB, gapB-encoded dehydrogenase, GapB-encoded protein
EC Number 1.2.1.72
CAS Registry Number
Comments This enzyme was originally thought to be a glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12), but this has since been disproved, as glyceraldehyde 3-phosphate is not a substrate [1,2]. Forms part of the pyridoxal-5′-phosphate coenzyme biosynthesis pathway in Escherichia coli, along with EC 1.1.1.290 (4-phosphoerythronate dehydrogenase), EC 2.6.1.52 (phosphoserine transaminase), EC 1.1.1.262 (4-hydroxythreonine-4-phosphate dehydrogenase), EC 2.6.99.2 (pyridoxine 5′-phosphate synthase) and EC 1.4.3.5 (pyridoxamine-phosphate oxidase).
Cofactor
History
Reactions D-erythrose 4-phosphate + NAD(+) + H(2)O = 4-phosphoerythronate + Nadh.

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