| Product Name |
FAD-AMP lyase (cyclizing) |
| Example Structure |
 |
| Synonyms |
dAK, Flavine-adenine-dinucleotide cyclase, FMN cyclase, FMN cyclase/dha kinase, Rivoflavin cyclic phosphate synthase, TKFC, triokinase/FMN cyclase |
| EC Number |
4.6.1.15 |
| CAS Registry Number |
208349-48-8 |
| Comments |
Requires Mn2+?or Co2+. While FAD was the best substrate tested [2], the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a?cis-bicyclic phosphodiester-pyranose fusion. The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. |
| Cofactor |
cobalt cation?or?Mn2+ |
| History |
|
| Reactions |
Fad = amp + riboflavin cyclic-4′,5′-phosphate. |
