FAD-dependent urate hydroxylase EC#: 1.14.13.113; ChemWhat Code: 1375341

Product Name FAD-dependent urate hydroxylase
Example Structure Example Structure of FAD-dependent urate hydroxylase EC#: 1.14.13.113
Synonyms FAD-dependent urate oxidase, flavin adenine dinucleotide-dependent urate oxidase, HpxO, HpxO enzyme, HpyO, urate hydroxylase, XCC0279
EC Number 1.14.13.113
CAS Registry Number
Comments A flavoprotein. The reaction is part of the purine catabolic pathway in the bacterium Klebsiella pneumoniae. The enzyme is different from EC 1.7.3.3, factor-independent urate hydroxylase, found in most plants, which produces hydrogen peroxide. The product of the enzyme is a substrate for EC 3.5.2.17, hydroxyisourate hydrolase.
Cofactor flavoprotein
History
Reactions Urate + Nadh + O(2) = 5-hydroxyisourate + NAD(+) + H(2)O.

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