ferredoxin:CoB-CoM heterodisulfide reductase EC#: 1.8.7.3; ChemWhat Code: 1374753

Product Name ferredoxin:CoB-CoM heterodisulfide reductase
Example Structure Example Structure of ferredoxin:CoB-CoM heterodisulfide reductase EC#: 1.8.7.3
Synonyms CoB-S-S-CoM reductase, Coenzyme B-Coenzyme M heterodisulfide reductase, hdrA1B1C1, hdrA2B2C2, HdrABC, HdrB, HdrB2, HdrB2C2, heterodisulfide reductase
EC Number 1.8.7.3
CAS Registry Number
Comments HdrABC is an enzyme complex that is found in most methanogens and catalyses the reduction of the CoB-CoM heterodisulfide back to CoB and CoM. HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit. One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyse EC 1.8.98.4, coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.98.5, H2:CoB-CoM heterodisulfide,ferredoxin reductase, EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase, and EC 1.8.98.1, dihydromethanophenazine:CoB-CoM heterodisulfide reductase.
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