ferredoxin:thioredoxin reductase EC#: 1.8.7.2; ChemWhat Code: 1374751

Product Name ferredoxin:thioredoxin reductase
Example Structure Example Structure of ferredoxin:thioredoxin reductase EC#: 1.8.7.2
Synonyms Fd:TRX reductase, FdR, ferredoxin disulfide reductase, FTR, FTRc, Ma_1659, protein modulase
EC Number 1.8.7.2
CAS Registry Number
Comments The enzyme contains a [4Fe-4S] cluster and internal disulfide. It forms a mixed disulfide with thioredoxin on one side, and docks ferredoxin on the other side, enabling two one-electron transfers. The reduced thioredoxins generated by the enzyme activate the Calvin cycle enzymes EC 3.1.3.11 (fructose-1,6-bisphosphatase), EC 3.1.3.37 (sedoheptulose-bisphosphatase) and EC 2.7.1.19 (phosphoribulokinase) as well as other chloroplast enzymes by disulfide reduction.
Cofactor iron-sulfur
History
Reactions 2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin + thioredoxin + 2 H(+).

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