ferric-chelate reductase (NADPH) EC#: 1.16.1.9; ChemWhat Code: 1375968
Product Name | ferric-chelate reductase (NADPH) |
Example Structure | |
Synonyms | FCR, FCR-LM, FCR-Os, Fe(III)-chelate reductase, ferredoxin-NADP(+) oxidoreductase, ferredoxin-NADP+ oxidoreductase, ferri-siderophore reductase, ferric chelate reductase, ferric reductase, ferric siderophore reductase, ferric-chelate reductase, FNR(S), FNRS, FRO1, FRO2, YqjH |
EC Number | 1.16.1.9 |
CAS Registry Number | |
Comments | Contains FAD. The enzyme, which is widespread among bacteria, catalyses the reduction of ferric iron bound to a variety of iron chelators (siderophores), including ferric triscatecholates and ferric dicitrate, resulting in the release of ferrous iron. The enzyme from the bacterium Escherichia coli has the highest efficiency with the hydrolysed ferric enterobactin complex ferric N-(2,3-dihydroxybenzoyl)-L-serine [3]. cf. EC 1.16.1.7, ferric-chelate reductase (NADH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H]. |
Cofactor | FAD |
History | |
Reactions | 2 Fe(II)-siderophore + NADP(+) + H(+) = 2 Fe(III)-siderophore + Nadph. |
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