flavanone 3-dioxygenase EC#: 1.14.11.9; ChemWhat Code: 1375081
| Product Name | flavanone 3-dioxygenase |
| Example Structure |  |
| Synonyms | (2S)-flavanone 3-hydroxylase, AaF3H, AcF3H, CsF3H, CtF3H, F3H, F3H protein, F3H1, F3H2, FHT, FHTPH, flavanone 3-dioxygenase, flavanone 3-hydroxylase, flavanone 3beta-hydroxylase, flavanone synthase I, flavanone-3-hydroxylase, FS I, LcF3H, naringenin 3-dioxygenase, naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating), oxygenase, flavanone 3-di-, PeF3H, PnF3H, RtF3H1, RtF3H2, VcF3H |
| EC Number | 1.14.11.9 |
| CAS Registry Number | 75991-43-4 |
| Comments | Requires Fe2+ and ascorbate. This plant enzyme catalyses an early step in the flavonoid biosynthesis pathway, leading to the production of flavanols and anthocyanins. Substrates include (2S)-naringenin, (2S)-eriodictyol, (2S)-dihydrotricetin and (2S)-pinocembrin. Some enzymes are bifuctional and also catalyse EC 1.14.20.6, flavonol synthase. |
| Cofactor | Fe2+;L-ascorbate |
| History | |
| Reactions | A (2S)-flavan-4-one + 2-oxoglutarate + O(2) = a (2R,3R)-dihydroflavonol + succinate + CO(2). |
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