fragilysin EC#: 3.4.24.74; ChemWhat Code: 1381077
| Product Name | fragilysin |
| Example Structure |  |
| Synonyms | Baceroides fragilis enterotoxin, Bacillus fragilis toxin, Bacteroides fragilis enterotoxin, Bacteroides fragilis toxin, BFT, BFT-1, BFT-2, BFT-3, Enterotoxin, FRA3, fragilysin-2, fragilysin-3, Korea-BFT, More, toxin-2 |
| EC Number | 3.4.24.74 |
| CAS Registry Number | 188596-63-6 |
| Comments | Thought to be a cause of diarrhoea in animals and humans. Hydrolyses extracellular matrix proteins, and disrupts tight junctions of intestinal epithelial cells. Also degrades intracellular, cytoskeletal proteins actin, myosin and others. In peptidase family?M10?(interstitial collagenase family). |
| Cofactor | Zn2+ |
| History | |
| Reactions | Broad proteolytic specificity, bonds hydrolyzed includes -Gly-|-Leu-, -Met-|-Leu-, -Phe-|-Leu-, -Cys-|-Leu-, -Leu-|-Gly-. |
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