fumarate reductase (CoM/CoB) EC#: 1.3.4.1; ChemWhat Code: 1374125
| Product Name | fumarate reductase (CoM/CoB) |
| Example Structure |  |
| Synonyms | Tfr, thiol:fumarate reductase |
| EC Number | 1.3.4.1 |
| CAS Registry Number | |
| Comments | The enzyme, isolated from the archaeon Methanobacterium thermoautotrophicum, is very oxygen sensitive. It cannot use reduced flavins, reduced coenzyme F420, or NAD(P)H as an electron donor. Distinct from EC 1.3.1.6 [fumarate reductase (NADH)], EC 1.3.5.1 [succinate dehydrogenase (ubiquinone)], and EC 1.3.5.4 [fumarate reductase (quinol)]. |
| Cofactor | |
| History | |
| Reactions | Fumarate + CoM + CoB = succinate + CoM-S-S-CoB. |
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