G-protein-coupled receptor kinase EC#: 2.7.11.16; ChemWhat Code: 1379020

Product Name G-protein-coupled receptor kinase
Example Structure Example Structure of G-protein-coupled receptor kinase EC#: 2.7.11.16
Synonyms by G protein-coupled receptor kinase 6, G protein-coupled receptor kinase, G protein-coupled receptor kinase 2, G protein-coupled receptor kinase 4, G protein-coupled receptor kinase 4gamma, G protein-coupled receptor kinase 5, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK4, G protein-coupled receptor kinase GRK5, G protein-coupled receptor kinase GRK6, G protein-coupled receptor kinase-6, G-protein coupled receptor kinase, G-protein coupled receptor kinase 5, G-protein coupled receptor kinase 6, G-protein-coupled receptor kinase 5, G-protein-coupled receptor kinase 6, GPCR kinase, GPCR kinase 2, GPCR kinase 4, GRK, GRK-6, GRK2, GRK3, GRK4, GRK4gamma, GRK5, GRK6, More
EC Number 2.7.11.16
CAS Registry Number
Comments Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. (cf. EC?2.7.11.14, rhodopsin kinase and EC?2.7.11.15, ¦Â-adrenergic-receptor kinase).
Cofactor
History
Reactions Atp + [G-protein-coupled receptor] = adp + [G-protein-coupled receptor] phosphate.

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