gamma-glutamylamine cyclotransferase EC#: 4.3.2.8; ChemWhat Code: 1382877
| Product Name | gamma-glutamylamine cyclotransferase |
| Example Structure |  |
| Synonyms | GGACT |
| EC Number | 4.3.2.8 |
| CAS Registry Number | |
| Comments | The enzyme, found in vertebrates, has no activity toward ¦Á-(¦Ã-L-glutamyl)-L-amino acids (cf. EC?4.3.2.9, ¦Ã-glutamylcyclotransferase). The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the ¦Ã-L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline. |
| Cofactor | |
| History | |
| Reactions | Epsilon-(gamma-L-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline. |
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