gamma-glutamylcyclotransferase EC#: 4.3.2.9; ChemWhat Code: 1382878

Product Name gamma-glutamylcyclotransferase
Example Structure Example Structure of gamma-glutamylcyclotransferase EC#: 4.3.2.9
Synonyms A2LD1, C7orf24, C7orf24 protein, cyclotransferase, gamma-glutamyl, gamma-glutamyl cyclotransferase, gamma-glutamyl cyclotransferases, gamma-glutamyl-amino acid cyclotransferase, gamma-glutamylamine cyclotransferase, gamma-glutamyltranspeptidase, gamma-L-glutamylcyclotransferase, GGACT, GGCT, GGCT2;1, GGCT2;2, GGCT2;3, L-glutamic cyclase, protein C7orf24, RipAY, RSp1022, {gamma}-glutamylamine cyclotransferase
EC Number 4.3.2.9
CAS Registry Number 9045-44-7
Comments The enzyme, found in animals and plants, acts on derivatives of?L-glutamate,?L-2-aminobutanoate,?L-alanine and glycine. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the ¦Á-amine of the?L-glutamyl residue, releasing it as the cyclic 5-oxo-L-proline. Formerly EC?2.3.2.4.
Cofactor
History
Reactions Alpha-(gamma-L-glutamyl)-L-amino acid = alpha-L-amino acid + 5-oxo-L- proline.

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